Benclin Gel 10g
Detail Description
Benclin Gel 10g – Specification
Requires Prescription: Yes
Generics:
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Clindamycin
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Benzoyl Peroxide
Used For:
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Acne vulgaris
How it Works:
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Clindamycin: A lincosamide antibacterial that inhibits bacterial protein synthesis, reducing acne-causing bacteria.
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Benzoyl Peroxide: An oxidizing agent with bactericidal and keratolytic effects; the precise mechanism of action is unknown.
Usage and Safety
Dosage:
As directed by the physician; applied topically to affected areas.
Side Effects:
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Mild local irritation
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Headache
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Reports of diarrhoea and colitis (discontinue immediately)
Drug Interactions:
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Avoid with erythromycin-containing products (possible antagonism with clindamycin).
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Clindamycin may enhance the action of neuromuscular blocking agents — use with caution.
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Avoid concurrent use with tretinoin, isotretinoin, tazarotene (may reduce efficacy and increase irritation) — if combination is needed, apply at different times (e.g., morning vs. evening).
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Avoid combining with topical sulphonamide-containing products — may cause temporary yellow/orange skin or hair discolouration.
Indication:
Topical treatment of acne vulgaris.
When Not to Use:
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Hypersensitivity to lincomycin, clindamycin, benzoyl peroxide, or formulation components.
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Patients with history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis (including pseudomembranous colitis).
Precautions:
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Avoid contact with mouth, eyes, lips, mucous membranes, or broken/irritated skin; rinse with water if accidental contact occurs.
Warnings
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Concomitant acne therapy caution — may cause severe cumulative irritation, especially with peeling or abrasive agents.
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Severe irritation (erythema, dryness, itching, stinging/burning) — discontinue use immediately.
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Photosensitivity — avoid sunlamps and prolonged sun exposure; use sunscreen and protective clothing if outdoors.
Pregnancy Category:
Consult physician before use.
Storage:
Store at room temperature, away from direct light and heat.