BH AV Sartan 14 Tablets 5mg + 80mg

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Medicine

Detail Description

Av-Sartan Tablets 5mg + 80mg (1 Strip = 7 Tablets) — Specification

Requires Prescription: Yes

Generics:

  • Amlodipine Besilate

  • Valsartan

Used For:

  • Hypertension

How it Works:
Amlodipine and Valsartan are antihypertensive agents with complementary mechanisms. Amlodipine, a calcium channel blocker, relaxes blood vessels by inhibiting calcium ion influx into vascular smooth muscle. Valsartan, an angiotensin II receptor antagonist, prevents angiotensin II from binding to its receptors, reducing vasoconstriction and sodium retention. Together, they have an additive effect in lowering blood pressure more effectively than either drug alone.

Usage & Safety

Dosage:

  • Amlodipine Besilate + Valsartan (as prescribed by physician)

Side Effects:

  • Nasopharyngitis, influenza, hypokalemia

  • Headache, asthenia, fatigue

  • Facial edema, flushing, hot flush

  • Peripheral & pitting edema

  • Anorexia, hypercalcemia, hyperlipidemia, hyperuricemia, hyponatremia

  • Dizziness, postural dizziness, paraesthesia, somnolence, visual impairment, vertigo

  • Palpitations, tachycardia, orthostatic hypotension

  • Cough, pharyngolaryngeal pain

  • Abdominal discomfort, upper abdominal pain, constipation, diarrhea, dry mouth, nausea

  • Erythema, rash

  • Arthralgia, back pain, joint swelling

Drug Interactions:

  • Other antihypertensive agents

  • Grapefruit or grapefruit juice

  • CYP3A4 inhibitors (protease inhibitors, azole antifungals, macrolides, verapamil, diltiazem)

  • CYP3A4 inducers (rifampicin, St. John’s Wort)

  • Simvastatin, lithium

  • Potassium-sparing diuretics, potassium supplements, potassium salt substitutes

  • NSAIDs

  • Rifampicin, cyclosporine, ritonavir

  • Sildenafil

Indication:

  • Treatment of hypertension

When Not to Use:

  • Known hypersensitivity to amlodipine, valsartan, dihydropyridines, or excipients

  • Severe hepatic impairment, biliary cirrhosis, or cholestasis

Precautions:

  • Use with caution in patients with unilateral/bilateral renal artery stenosis or stenosis of a solitary kidney (may increase blood urea and creatinine levels)

Warnings:

  1. Use cautiously with potassium-raising agents; monitor potassium levels regularly.

  2. Safety and efficacy of amlodipine in hypertensive crisis have not been established.

  3. Angioedema (swelling of face, lips, tongue, or airway) has been reported; discontinue immediately if it occurs.

Pregnancy Category:

  • Always consult a physician before use

Storage:

  • Store at room temperature, away from direct light and heat