BH Febrol 200 Tablets
Detail Description
Febrol Tablets 500 mg Specification
Requires Prescription: No
Generics: Paracetamol
Used For: Pain & Fever
How it works:
Paracetamol exerts a central analgesic effect, likely mediated through activation of descending serotonergic pathways. Its exact mechanism is debated — it may involve inhibition of prostaglandin synthesis or effects of an active metabolite on cannabinoid receptors.
Usage and Safety
Dosage: Paracetamol (as prescribed by a physician or per packaging instructions)
Side Effects:
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Thrombocytopenia
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Anaphylaxis
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Cutaneous hypersensitivity reactions (e.g., rash, angioedema, Stevens–Johnson syndrome, toxic epidermal necrolysis)
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Bronchospasm in aspirin/NSAID-sensitive patients
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Hepatic dysfunction
Drug Interactions:
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Prolonged regular daily use may enhance the anticoagulant effect of warfarin and other coumarins, increasing bleeding risk.
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Occasional doses usually have no significant effect.
Indication:
Provides fast and effective relief from:
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Headache
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Migraine pain
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Joint pain (Osteoarthritis)
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Muscle aches
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Toothache
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Period pain
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Fever
When Not to Use:
Contraindicated in patients with hypersensitivity to paracetamol or any excipients.
Precautions & Warnings
Precaution:
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Contains paracetamol — avoid combining with other paracetamol-containing products to prevent overdose.
Warnings:
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Patients with underlying liver disease are at higher risk of liver damage.
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Hepatic dysfunction/failure reported in patients with depleted glutathione (malnutrition, anorexia, low BMI, chronic heavy alcohol use).
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In glutathione-depleted states (e.g., sepsis), paracetamol may increase metabolic acidosis risk.
Pregnancy Category: Consult a physician before use.
Storage: Store at room temperature, away from direct light and heat.