BH Inocef Injection 1 Box

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Detail Description

Inocef IV Injection 1000 mg (1 Box = 1 Injection) – Specification

Requires Prescription: Yes

Generics: Ceftriaxone Sodium

Used For: Bacterial infections

How it Works:
Ceftriaxone inhibits mucopeptide synthesis in the bacterial cell wall. Its beta-lactam moiety binds to bacterial enzymes (carboxypeptidases, endopeptidases, and transpeptidases) involved in cell wall synthesis and division, causing defective cell walls and bacterial death.

Usage and Safety

Dosage: Ceftriaxone Sodium (as prescribed by physician)

Side Effects:

  • Hypersensitivity reactions (allergic skin reactions, anaphylaxis)

  • Secondary infections with yeast, fungi, or resistant organisms

  • Blood cell changes: neutropenia, leucopenia, eosinophilia, thrombocytopenia, anaemia (including haemolytic anaemia)

  • Slight prolongation of prothrombin time

  • Headache, dizziness

  • Increase in liver enzymes (AST, ALT, alkaline phosphatase)

  • Rigors, fever

Drug Interactions:

  • Calcium-containing IV solutions

  • Oral hormonal contraceptives

Indications

Treatment of infections caused by susceptible organisms, including:

  • Lower respiratory tract infections

  • Acute bacterial otitis media

  • Skin and skin structure infections

  • Urinary tract infections (complicated and uncomplicated)

When Not to Use

Do not use in patients with:

  • Hypersensitivity to ceftriaxone or other cephalosporins

  • History of immediate/severe hypersensitivity to penicillin or other beta-lactam drugs

  • Premature newborns up to a corrected age of 41 weeks (gestation + life weeks)

Precautions

  • Assess history of hypersensitivity to cephalosporins, penicillins, or other drugs before starting therapy

Warnings

  1. May cause immune-mediated haemolytic anaemia

  2. Patients with low vitamin K stores (e.g., liver disease, malnutrition) may require prothrombin time monitoring and vitamin K supplementation

  3. Prolonged use may cause overgrowth of non-susceptible organisms; monitor for superinfection

Pregnancy Category: Consult physician before use
Storage: Store at room temperature, away from direct light and heat