Biflor 10 Sachets

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Detail Description

Biflor Sachet 250 mg (1 Box = 10 Sachets) — Specification

Requires Prescription: Yes

Generics: Saccharomyces boulardii

Used For: Diarrhoea

How it works:
Saccharomyces boulardii is a probiotic (“friendly germ”) used to treat diarrheal illnesses, maintain normal bowel function, and promote intestinal health. It helps restore normal bowel flora, inhibits harmful bacteria growth, stimulates local immunity, and promotes water reabsorption in the colon.


Usage and Safety

  • Dosage: Saccharomyces boulardii (as per physician’s recommendation)

  • Side Effects:

    • Rare: Fungemia, serious allergic reactions (rash, swelling, severe dizziness, breathing difficulty)

    • Uncommon: Constipation, flatulence, bloating, increased thirst

  • Drug Interactions:
    Systemic antifungals (fluconazole, itraconazole, terbinafine) reduce efficacy — avoid concomitant use.


Indications:

  • Treatment & prevention of diarrhea (including rota-viral diarrhea in children)

  • Antibiotic-associated diarrhea (including Clostridium difficile–associated diarrhea and recurrent colitis)

  • Traveler’s diarrhea, diarrhea from tube feedings

  • Diarrhea linked to IBS, IBD (Crohn’s, ulcerative colitis), and bacterial overgrowth in short bowel syndrome


When not to use:

  • Immunocompromised patients

  • GI wall perforation

  • Allergy to yeast or yeast-based products

  • Patients on systemic antifungals

  • Critically ill patients or those with central venous catheters


Precautions:

  • Rare risk of Saccharomyces fungemia, especially in critically ill or immunocompromised patients, or those with central lines

  • Increased environmental risk in ICU due to air contamination when opening sachets


Warnings:

  1. Avoid use in critical care settings without strict infection control

  2. Do not use if allergic to yeast

  3. Not a standalone treatment for C. difficile — must be combined with recommended antibiotics


Pregnancy Category: Consult a physician before use

Storage: Store at room temperature, away from direct light and heat